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Biotechnology: An Overview and Evaluation


Article # : 13155 

Section : MODERN THOUGHT
Issue Date : 11 / 1987  3,945 Words
Author : Van Rensselaer Potter
Van Rensselaer Potter is Hilldale Professor Emeritus of Oncology at the University of Wisconsin Medical School in Madison.

       Biotechnology is a highly specialized field that is largely in the hands of molecular biologists and genetic engineers who have left their ivory towers to become businessmen, hoping to reap fabulous profits. In more than one sense they have embraced the goals of the medieval alchemists. This article addresses how biotechnology evolved, how the technological control of life processes impinges on the technology of birth control, and how bioethics became the whistle-blower on the exercise of biological power.
       
        The prefix "bio-" (pertaining to Life) is finding increasing use. It is not a word that can stand alone, but it modifies the meaning of a number of words that have a prior history. Many of these words describe academic disciplines. They name departments in universities and designate Ph.D. fields. An early example of a clearly defined discipline is chemistry, dating back to 1200, when alchemists were identifying chemical elements, attempting to convert base metals into gold, and trying to find a substance that would cure all ailments and enable people to live forever. Shortly after chemistry became an established profession, departments of agricultural chemistry in land-grant colleges and physiological chemistry in medical schools split off from chemistry departments and created their separate doctoral requirements. In the 1930s many of these departments changed their name to biochemistry, often overcoming considerable opposition within their ranks.
       
        Similarly, physics as a discipline began in ancient Greece, with Archimedes a well-known representative. Physics is most easily defined as the study of the natural laws that govern nonliving objects, with Isaac Newton and Albert Einstein as its recent proponents. Rather suddenly, after powerful tools such as the ultracentrifuge and electron microscope became available, physicists applied their study to living material. The new venture matured as a discipline and was named biophysics in the late 1950s. Again departments were created and Ph.D.'s were granted.
       
        In the case of both biochemistry and biophysics, the flow was from the parent discipline into the new ventures. The effort was interdisciplinary or even multidisciplinary. The mating of chemistry and biology or of physics and biology yielded biochemistry and biophysics respectively. The interdisciplinary effort became a new discipline with a new label, although in many cases, especially in biophysics, a broad knowledge of biology was woefully lacking. But, no matter; results were spectacular.
       
        Biology was the first academic
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